DOC of Bacterial STDs

Drug of choice for Bacterial STDs

Disease	Treatment	Recommending authority
Early syphilis- First 2 years (Primary/Secondary/Early latent)	Inj. Benzathine Penicillin 2.4 MU im single dose	CDC
Late syphilis- After 2 years (Late latent/Tertiary except neurosyphilis)	Inj. Benzathine Penicillin 2.4 MU im three doses at weekly intervals	CDC
Neurosyphilis	Inj. Crystalline aqueous penicillin 3-4 MU 4 hourly for 14 days	CDC
Chancroid	Tab Azithromycin 1gm single dose	WHO/ CDC/ NACO/ CEG
LGV	Doxycycline 100 mg BD for 21 days	WHO/CDC
Donovanosis	Preferred: Doxy 100 mg BD at least 3 weeks for until lesions heal Alternative: Tab Azithromycin 1 gm/week at least 3 weeks, but preferable till ulcer heals	CDC
	Tab Azithromycin 1 gm stat followed by 500 mg OD till ulcer heals  or Doxy 100 mg BD at least 3 weeks for until lesions heal	WHO
Bacterial vaginosis (Note it is not an STD)	Tab Metronidazole 400 mg BD for 7 days (preferred) Alternatives: Tab Metro 2gm single dose of Tab Tinidazole 2 gm single dose	CDC
Gonorrhea	Tab Cefixime 400 mg single dose or  Inj. Ceftriaxone 250 mg im stat	CDC/WHO/IUSTI